BDBM315520 US10172858, Table 2.16::US9828378, # 16
SMILES CC(C)n1nc(-c2cc3cc(O)cc(F)c3[nH]2)c2c(N)ncnc12
InChI Key InChIKey=LUKIMGGLSGHDAN-UHFFFAOYSA-N
Data 15 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 315520
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Intellikine
US Patent
Intellikine
US Patent
Affinity DataIC50: <500nMAssay Description:This assay is relatively simple, reasonably sensitive, and the peptide substrate can be adjusted both in terms of sequence and concentration to meet ...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Intellikine
US Patent
Intellikine
US Patent
Affinity DataIC50: <500nMAssay Description:Class I PI3-Ks can be either purchased (p110α/p85α, p110β/p85α, p110δ/p85α from Upstate, and p110γ from Sigma) or...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Intellikine
US Patent
Intellikine
US Patent
Affinity DataIC50: 100nMAssay Description:Inhibition of human PI3Kgamma preincubated for 15 mins followed by ATP addition measured after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair