BDBM553963 US11325906, Example 26

SMILES CNC(=O)c1ccc(N2CCN(Cc3ccc4nc(CCF)c(=O)[nH]c4c3)CC2)c(F)n1

InChI Key InChIKey=SUZKBBJSZAJIDV-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 553963   

TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM553963(US11325906, Example 26)
Affinity DataIC50:  5nMAssay Description:PARP1: Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent