BDBM514554 US11096924, DASH-inhibitors 5363::US11583516, Cmpd ID 5363

SMILES CC1(C)CCN[C@@H]1C(=O)N1CCC[C@H]1B(O)O

InChI Key InChIKey=XBIIDVIXTFCFMM-DTWKUNHWSA-N

Data  21 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 514554   

TargetProlyl endopeptidase FAP(Homo sapiens (Human))
Trustees of Tufts College

US Patent
LigandPNGBDBM514554(US11096924, DASH-inhibitors 5363 | US11583516, Cmp...)
Affinity DataIC50:  3.20E+4nMAssay Description:EnzymesRecombinant human DPPIV (R&D Systems, Cat. No. 1180-SE)Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527)Recombinant human DPP9 (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProlyl endopeptidase FAP(Homo sapiens (Human))
Trustees of Tufts College

US Patent
LigandPNGBDBM514554(US11096924, DASH-inhibitors 5363 | US11583516, Cmp...)
Affinity DataIC50:  32nMAssay Description:This assay is described in Bachovchin et al. Nature Chemical Biology 10, 656-663 (2014). Briefly, purified enzymes are coupled to Luminex microsphere...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProlyl endopeptidase FAP(Homo sapiens (Human))
Trustees of Tufts College

US Patent
LigandPNGBDBM514554(US11096924, DASH-inhibitors 5363 | US11583516, Cmp...)
Affinity DataIC50:  32nMAssay Description:Materials: Enzymes Recombinant human DPPIV (R&D Systems, Cat. No. 1180-SE). Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527). Recombin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent