BDBM22960 2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl-1H-indol-3-yl}-N-[4-(methylsulfanyl)phenyl]acetamide::CHEMBL96011::Indomethacin derivative, 13
SMILES COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(=O)Nc3ccc(SC)cc3)c2c1
InChI Key InChIKey=HSXMIESEORMVHU-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 22960
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Vanderbilt University School of Medicine
Curated by ChEMBL
Vanderbilt University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 120nMAssay Description:In vitro inhibitory activity against human Prostaglandin G/H synthase 2 (66 nM) using [14C]-AA (50 uM) was determinedMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Vanderbilt University School of Medicine
Curated by ChEMBL
Vanderbilt University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 120nMT: 2°CAssay Description:For the time-dependent inhibition studies, COX enzyme was incubated with test compounds for 20 min and then analyzed for remaining COX activity by tr...More data for this Ligand-Target Pair