BDBM50007203 CHEMBL3237875

SMILES COc1ccc(C[C@H](NC(=O)[C@H](C)NC(=O)CN2CCOCC2)C(=O)N[C@@H](Cc2ccccc2)C(=O)[C@@]2(C)CO2)cc1

InChI Key InChIKey=WQAVPPWWLLVGFK-VTNASVEKSA-N

Data  56 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50007203   

TargetProteasome subunit beta type-2(Homo sapiens (Human))
Kezar Life Sciences

Curated by ChEMBL
LigandPNGBDBM50007203(CHEMBL3237875)
Affinity DataIC50:  930nMAssay Description:Inhibition of proteasome beta2 in human MOLT4 cell lysate after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-2(Homo sapiens (Human))
Kezar Life Sciences

Curated by ChEMBL
LigandPNGBDBM50007203(CHEMBL3237875)
Affinity DataIC50:  4.70E+3nMAssay Description:Inhibition of human 20S constitutive proteasome beta-2 using BocLRR-AMC as substrate incubated for 15 mins measured for 45 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-2(Homo sapiens (Human))
Kezar Life Sciences

Curated by ChEMBL
LigandPNGBDBM50007203(CHEMBL3237875)
Affinity DataIC50:  927nMAssay Description:Inhibition of 20S proteosome beta 2 in human MOLT4 cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-2(Mus musculus)
Kezar Life Sciences

Curated by ChEMBL
LigandPNGBDBM50007203(CHEMBL3237875)
Affinity DataIC50:  913nMAssay Description:Inhibition of 20S proteosome beta 2 in mouse A20 cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-2(Homo sapiens (Human))
Kezar Life Sciences

Curated by ChEMBL
LigandPNGBDBM50007203(CHEMBL3237875)
Affinity DataIC50:  927nMAssay Description:Inhibition of 20S proteosome beta 2 in human MOLT4 cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-2(Mus musculus)
Kezar Life Sciences

Curated by ChEMBL
LigandPNGBDBM50007203(CHEMBL3237875)
Affinity DataIC50:  913nMAssay Description:Inhibition of 20S proteosome beta 2 in mouse A20 cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed