BDBM388309 US10294246, Compound No. 6
SMILES OB(O)[C@H](Cc1coc2ccccc12)NC(=O)Cc1ccccc1
InChI Key InChIKey=XRRMRPLIEUPSEG-KRWDZBQOSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 388309
Affinity DataIC50: <50nMAssay Description:Measurement of LMP7 inhibition is performed in 384 well format based on fluorescence intensity assay.Purified human immunoproteasome (0.25 nM) and se...More data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of 20S immunoproteasome beta-5i subunit in human PBMC using Ac-ANW-luciferin substrate preincubated for 2 hrs followed by substrate additi...More data for this Ligand-Target Pair
Affinity DataIC50: 2.10nMAssay Description:Inhibition of human 20S immunoproteasome beta-5i subunit using Suc-LLVY-AMC as substrate preincubated for 2 hrs followed by substrate addition and me...More data for this Ligand-Target Pair