BDBM488403 2-(4-Amino-1-tert-butyl-pyrazolo[3,4-d]pyrimidin- 3-yl)-3-chloro-N-[1-(2-hydroxyethyl)pyrazol-3-yl]- 1H-indole-6-carboxamide::US10954241, Example 43::US11548896, Example 43
SMILES CC(C)(C)n1nc(-c2[nH]c3cc(ccc3c2Cl)C(=O)Nc2ccn(CCO)n2)c2c(N)ncnc12
InChI Key InChIKey=ACNNJWMMLBYERQ-UHFFFAOYSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 488403
Affinity DataIC50: 5.66nMAssay Description:Kinase activity was detected using CisBio HTRF kinEASE kit based on time-resolved fluorescence transfer (FRET). The assay was performed in 384-well w...More data for this Ligand-Target Pair
Affinity DataIC50: 5.66nMAssay Description:RET, RETV804M and KDR: Kinase activity was detected using CisBio HTRF kinEASE kit based on time-resolved fluorescence transfer (FRET). The assay was ...More data for this Ligand-Target Pair