BDBM296709 US10112942, Example 444::US10137124, Example 444::US10172851, Example 444::US10555944, Example 444::US10953005, Example 444
SMILES COc1ccc(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(OCCC3CCN(C)CC3)cn3ncc(C#N)c23)cn1
InChI Key InChIKey=HBHWJMVASKPSHO-UHFFFAOYSA-N
Data 15 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 296709
TargetProto-oncogene tyrosine-protein kinase receptor Ret [V804M](Homo sapiens (Human))
Array Biopharma
US Patent
Array Biopharma
US Patent
Affinity DataIC50: 16.1nMAssay Description:Compounds of Formula I were screened for their ability to inhibit wildtype and V804M mutant RET kinase using CisBio's HTRF® KinEASE¿-TK assay tec...More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase receptor Ret [V804M](Homo sapiens (Human))
Array Biopharma
US Patent
Array Biopharma
US Patent