BDBM488429 2-{4-Amino-1-tert-butyl-1H-pyrazolo[3,4- d]pyrimidin-3-yl}-3,5-dichloro-N-methyl-1H- indole-6-carboxamide::US10954241, Example 69::US11548896, Example 69
SMILES CNC(=O)c1cc2[nH]c(c(Cl)c2cc1Cl)-c1nn(c2ncnc(N)c12)C(C)(C)C
InChI Key InChIKey=YPHHJHFATSNKHX-UHFFFAOYSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 488429
TargetProto-oncogene tyrosine-protein kinase receptor Ret [V804M](Human)
Cancer Research Technology
US Patent
Cancer Research Technology
US Patent
Affinity DataIC50: 131nMAssay Description:RET, RETV804M and KDR: Kinase activity was detected using CisBio HTRF kinEASE kit based on time-resolved fluorescence transfer (FRET). The assay was ...More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase receptor Ret [V804M](Human)
Cancer Research Technology
US Patent
Cancer Research Technology
US Patent
Affinity DataIC50: 131nMAssay Description:Kinase activity was detected using CisBio HTRF kinEASE kit based on time-resolved fluorescence transfer (FRET). The assay was performed in 384-well w...More data for this Ligand-Target Pair