BDBM580839 5-(3-morpholino-5-((tetrahydrofuran-3- yl)sulfonyl)phenyl)pyrimidin-2-amine::US11492348, Compound 51
SMILES Nc1ncc(cn1)-c1cc(cc(c1)S(=O)(=O)C1CCOC1)N1CCOCC1
InChI Key InChIKey=JOSFJDYSRMQQQE-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 580839
TargetRAC-alpha serine/threonine-protein kinase [1-472,474-480](Homo sapiens (Human))
Neuropore Therapies
US Patent
Neuropore Therapies
US Patent
Affinity DataIC50: 2.12E+3nMAssay Description:Inhibition of the PI3K-AKT-mTOR pathway was measured by quantifying the loss of (Ser-473) pAKT using AlphaScreen (Perkin Elmer). B103 (Rat Neuroblast...More data for this Ligand-Target Pair