BDBM50131841 CHEMBL3633143

SMILES COc1cc(ccc1Nc1ncc2c(C)cc(=O)n(-c3cccc(NC(=O)C=C)c3)c2n1)N1CCN(C)CC1

InChI Key InChIKey=VJQPNQROUWVJQN-UHFFFAOYSA-N

Data  4 IC50  3 EC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50131841   

TargetRAC-gamma serine/threonine-protein kinase(Homo sapiens (Human))
Jinan University

Curated by ChEMBL
LigandPNGBDBM50131841(CHEMBL3633143)
Affinity DataEC50: >1.00E+3nMAssay Description:Induction of AKT3 degradation in human NCI-H1975 cells assessed as reduction in AKT3 protein level incubated for 24 hrs under serum free medium by We...More data for this Ligand-Target Pair
In DepthDetails PubMed