BDBM202666 US10245267, Example 11::US10709712, Example 11::US9242969, 11::US9694016, 11

SMILES Cc1ccc(cc1-c1cc(nc(n1)N1CCOCC1)N1CCOCC1)C(=O)Nc1cccc(c1)C(F)(F)F

InChI Key InChIKey=ZNVCVMODGVQVMO-UHFFFAOYSA-N

Data  18 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 202666   

TargetRAF proto-oncogene serine/threonine-protein kinase [325-648](Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM202666(US10245267, Example 11 | US10709712, Example 11 | ...)
Affinity DataIC50:  0.580nMAssay Description:C-Raf TR refers to a truncated C-Raf protein, a Δ1-324 deletion mutant.C-Raf FL refers to the full-length C-Raf protein.Full length MEK1 with an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent