BDBM50555575 C-18112003-G::GNS-1480::GNS1480::JNJ-73841937-AAA::Lazertinib::US11267810, Example T-6::YH-25448::Yh25448

SMILES COc1cc(N2CCOCC2)c(NC(=O)C=C)cc1Nc1nccc(n1)-n1cc(CN(C)C)c(n1)-c1ccccc1

InChI Key InChIKey=RRMJMHOQSALEJJ-UHFFFAOYSA-N

Data  3 KI  14 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50555575   

TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
The State University Of New York

Curated by ChEMBL
LigandPNGBDBM50555575(C-18112003-G | GNS-1480 | GNS1480 | JNJ-73841937-A...)
Affinity DataKi:  437nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged HER2 wild type (679 to 1255 residues) expressed in baculovirus infected Sf9 insect cells using ...More data for this Ligand-Target Pair
In DepthDetails PubMed