BDBM50233241 CHEMBL4071080
SMILES CN1c2ccccc2OC[C@H](NC(=O)c2cc(Cc3ccccc3)ccn2)C1=O
InChI Key InChIKey=BYZLFSSTPKOLGN-IBGZPJMESA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50233241
TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Queen Mary University of London
Curated by ChEMBL
Queen Mary University of London
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of RIP1 in human U937 cells assessed as reduction in TNFalpha/QVD-Oph-induced necrosis after 24 hrs by Cell Titer-Glo luminescent cell via...More data for this Ligand-Target Pair
TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Queen Mary University of London
Curated by ChEMBL
Queen Mary University of London
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of human RIP1 (1 to 375 residues) expressed in baculovirus infected insect cells preincubated for 1 hr followed by ATP addition measured a...More data for this Ligand-Target Pair