BDBM50001584 CHEMBL3237442::US8841312, 1

SMILES C1CCC(C1)n1c2cnccc2c2cnc(Nc3ccc(cn3)N3CCNCC3)nc12

InChI Key InChIKey=MCPPMOSBWNMSOA-UHFFFAOYSA-N

Data  6 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50001584   

TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50001584(CHEMBL3237442 | US8841312, 1)
Affinity DataIC50:  14nMAssay Description:Inhibition of GST-fused human FLT3 cytoplasmic domain (amino acids 564 to 993) using Ulight-JAK1 as substrate after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed