BDBM622516 US20230312583, Compound I-12

SMILES COc1cc(Nc2ncc3ccc4ncn(C(C)C)c4c3n2)ncc1N1CC2CCC1CN2

InChI Key InChIKey=KOSUFZUQHXDTAI-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 622516   

TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Shengke Pharmaceuticals (Jiangsu)

US Patent
LigandPNGBDBM622516(US20230312583, Compound I-12)
Affinity DataIC50:  1.25nMAssay Description:Compounds of the present disclosure were tested in a 10-dose IC50 mode with a 3-fold serial dilution starting from 0.5 μM, and the control compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent