BDBM484443 US10934285, Example 29
SMILES CC[C@@H]1OCC2(CCN(CC2)c2cnc(Sc3cccc(NC(=O)c4c(O)nc5CCCCn5c4=O)c3Cl)c(N)n2)[C@@H]1N
InChI Key InChIKey=LQTJBJPFUSKYGY-GAJHUEQPSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 484443
Affinity DataIC50: 12nMAssay Description:The inhibition of SHP2 by compounds of the invention (concentrations varying from 0.003-100 μM) was monitored using an assay in which 0.5 nM of ...More data for this Ligand-Target Pair