BDBM50509365 CHEMBL4564337

SMILES COc1cc2c(c[nH]c2cc1Br)-c1cnc(o1)-c1ccc[nH]1

InChI Key InChIKey=XCOSAQGGGZDYJN-UHFFFAOYSA-N

Data  17 IC50  19 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50509365   

TargetSerine/threonine-protein kinase 17B(Homo sapiens (Human))
Uit - The Arctic University of Norway

Curated by ChEMBL
LigandPNGBDBM50509365(CHEMBL4564337)
Affinity DataKd:  390nMAssay Description:Binding affinity to wild-type human full length DRAK2 (M1 to C372 residues) expressed in bacterial expression system by active-site directed competit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase 17B(Homo sapiens (Human))
Uit - The Arctic University of Norway

Curated by ChEMBL
LigandPNGBDBM50509365(CHEMBL4564337)
Affinity DataIC50:  9.80E+3nMAssay Description:Inhibition of Alexa Fluor 647-labeled ATP competitive kinase tracer binding to GST-tagged DRAK2 (unknown origin) by FRET based cell free ATP-competit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase 17B(Homo sapiens (Human))
Uit - The Arctic University of Norway

Curated by ChEMBL
LigandPNGBDBM50509365(CHEMBL4564337)
Affinity DataIC50:  500nMAssay Description:Inhibition of DRAK2 (unknown origin) expressed in HEK293 cells by NanoLuc-luciferase reporter based intracellular ATP competitiveness assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed