BDBM300143 US9593100, Compound 24
SMILES COC(=O)N[C@@H](C)CNc1nccc(n1)-c1cn(nc1-c1cc(F)cc(NS(=O)(=O)C2CC2)c1F)C(C)C
InChI Key InChIKey=JUTDCRUMEUQOPM-AWEZNQCLSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 300143
Affinity DataIC50: 23nMAssay Description:B-Raf (V600E; 4 pM) and biotinylated Mek (kinase dead; 10 nM) were combined at 2× final concentrations in assay buffer (50 mM Tris, pH 7.5, 15 mM MgC...More data for this Ligand-Target Pair