BDBM50556315 CHEMBL4745330

SMILES COc1cccc2nc(Nc3cccc(NC(=O)c4ccc(N5CCN(C)CC5)c(c4)C(F)(F)F)c3)ccc12

InChI Key InChIKey=XCHCIVYQULUSFP-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50556315   

TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Korea Institute of Science & Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM50556315(CHEMBL4745330)
Affinity DataIC50:  1.46E+3nMAssay Description:Inhibition of human BRAF V600E mutant using MEK1 (K97R) as substrate in presence of [gamma-33P]ATP by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Korea Institute of Science & Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM50556315(CHEMBL4745330)
Affinity DataIC50:  2.94E+3nMAssay Description:Inhibition of human BRAF using MEK1 (K97R) as substrate in presence of [gamma-33P]ATP by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed