BDBM26682 2-amino-6-(4-hydroxyphenyl)-4-phenylpyridine-3-carbonitrile::2-amino-6-(4-ketocyclohexa-2,5-dien-1-ylidene)-4-phenyl-1H-pyridine-3-carbonitrile::2-aminopyridine-3-carbonitrile, 10

SMILES Nc1nc(cc(-c2ccccc2)c1C#N)-c1ccc(O)cc1

InChI Key InChIKey=VVFRJCXNTHXSOG-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 26682   

TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Valeant Pharmaceuticals Research and Development

LigandPNGBDBM26682(2-amino-6-(4-hydroxyphenyl)-4-phenylpyridine-3-car...)
Affinity DataIC50:  4.41E+3nMpH: 7.5 T: 2°CAssay Description:PIM-1 kinase activity was evaluated using calf thymus histones as the substrate in a 96-well filter plate format. After incubation, the plate was was...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed