BDBM291220 N-{4-[(3R,4R,5S)-3-Amino-5-cyclopropyl-4-hydroxypiperidin-1-yl]pyridin-3-yl}-7-(3-oxa-9-azaspiro[5.5]undec-9-yl)-1,5-naphthyridine-2-carboxamide::US9580418, Example 40::US9890162, Example 40
SMILES N[C@@H]1CN(C[C@H](C2CC2)[C@H]1O)c1ccncc1NC(=O)c1ccc2ncc(cc2n1)N1CCC2(CCOCC2)CC1
InChI Key InChIKey=FAIGDONBKDGOGD-VDWGHMIBSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 291220
Affinity DataIC50: <10nMpH: 7.5 T: 25°CAssay Description:Pim-1 and Pim-3 kinase assays-20 μL reactions were run in white 384 well polystyrene plates dotted with 0.8 μL compound/DMSO in the assay b...More data for this Ligand-Target Pair
Affinity DataIC50: <10nMAssay Description:Pim-1 and Pim-3 kinase assays-20 uL reactions were run in white 384 well polystyrene plates dotted with 0.8 uL compound/DMSO in the assay buffer (50 ...More data for this Ligand-Target Pair