BDBM50250267 CHEMBL1882801
SMILES Clc1ccc(C(=O)NC2CCN(Cc3ccccc3)CC2)c(Cl)c1
InChI Key InChIKey=OIDACLQVAGIDMT-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50250267
TargetSodium- and chloride-dependent GABA transporter 1(Homo sapiens (Human))
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of human GAT1 expresses in tsA201 cells assessed as reduction in [3H]GABA uptake after 3 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of mouse GAT1 expressed in HEK293 cells assessed as reduction in [3H]GABA uptake after 3 mins by scintillation counting methodMore data for this Ligand-Target Pair