BDBM50337911 (+/-)-1-(1-(3,4-dichlorophenyl)cyclohexyl)-N,N-dimethylethanamine::1-(1-(3,4-dichlorophenyl)cyclohexyl)-N,N-dimethylethanamine::CHEMBL1684047::CHEMBL1684058::US10562878, Compound 43

SMILES CC(N(C)C)C1(CCCCC1)c1ccc(Cl)c(Cl)c1

InChI Key InChIKey=OBWKCACUZGJXHN-UHFFFAOYSA-N

Data  21 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50337911   

TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
School Of Medicine Of University Of Electronic Science And Technology Of China

Curated by ChEMBL
LigandPNGBDBM50337911((+/-)-1-(1-(3,4-dichlorophenyl)cyclohexyl)-N,N-dim...)
Affinity DataIC50:  12nMAssay Description:Inhibition of recombinant human 5-HT transporter expressed in HEK293 cells assessed as reduction in [3H]-5-HT reuptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
School Of Medicine Of University Of Electronic Science And Technology Of China

Curated by ChEMBL
LigandPNGBDBM50337911((+/-)-1-(1-(3,4-dichlorophenyl)cyclohexyl)-N,N-dim...)
Affinity DataIC50:  15nMAssay Description:Inhibition of [3H]serotonin reuptake at human recombinant SERT expressed in LLC-PK1 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
School Of Medicine Of University Of Electronic Science And Technology Of China

Curated by ChEMBL
LigandPNGBDBM50337911((+/-)-1-(1-(3,4-dichlorophenyl)cyclohexyl)-N,N-dim...)
Affinity DataIC50:  12nMAssay Description:Inhibition of [3H]serotonin reuptake at human recombinant SERT expressed in LLC-PK1 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
School Of Medicine Of University Of Electronic Science And Technology Of China

Curated by ChEMBL
LigandPNGBDBM50337911((+/-)-1-(1-(3,4-dichlorophenyl)cyclohexyl)-N,N-dim...)
Affinity DataIC50:  15nMAssay Description:Inhibition of [3H]serotonin reuptake at human recombinant SERT expressed in LLC-PK1 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
School Of Medicine Of University Of Electronic Science And Technology Of China

Curated by ChEMBL
LigandPNGBDBM50337911((+/-)-1-(1-(3,4-dichlorophenyl)cyclohexyl)-N,N-dim...)
Affinity DataIC50:  15nMAssay Description:Inhibition of human serotonin reuptake transporter was assayed using the recombinant human serotonin transporter expressed in HEK-293 cells. HEK-293 ...More data for this Ligand-Target Pair
In DepthDetails US Patent