BDBM523757 US11136312, Compound MM-I-87

SMILES Fc1ccc2c(Cc3nnc(Cc4cccc(c4)C(F)(F)F)n3CCCc3c[nH]cn3)c[nH]c2c1

InChI Key InChIKey=HRMZYZYVRKSGFD-UHFFFAOYSA-N

Data  7 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 523757   

TargetSomatostatin receptor type 3(Homo sapiens (Human))
Southern Illinois University Edwardsville

Curated by ChEMBL
LigandPNGBDBM523757(US11136312, Compound MM-I-87)
Affinity DataKi:  1.61E+3nMAssay Description:Displacement of [125I]-Tyr-SRIF 14 from SST3 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSomatostatin receptor type 3(Homo sapiens (Human))
Southern Illinois University Edwardsville

Curated by ChEMBL
LigandPNGBDBM523757(US11136312, Compound MM-I-87)
Affinity DataEC50:  0.249nMAssay Description:Measurement of forskolin stimulated inhibition of cAMP was performed via time-resolved fluorescence resonance energy transfer (TR-FRET) LANCE assay (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent