BDBM523764 US11136312, Compound SK-I-55

SMILES COc1ccc2[nH]cc(Cc3nnc(Cc4ccc(F)cc4)n3CCCc3c[nH]cn3)c2c1

InChI Key InChIKey=AOCQTKJNMPPTJU-UHFFFAOYSA-N

Data  10 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 523764   

TargetSomatostatin receptor type 4(Homo sapiens (Human))
Board of Trustees of The Southern Illinois University

US Patent
LigandPNGBDBM523764(US11136312, Compound SK-I-55)
Affinity DataKi:  2.79nMAssay Description:Competitive radioligand binding experiments were performed using MEMBRANE TARGET Systems (Perkin-Elmer, Boston, Mass.) for human somatostatin recepto...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSomatostatin receptor type 4(Homo sapiens (Human))
Board of Trustees of The Southern Illinois University

US Patent
LigandPNGBDBM523764(US11136312, Compound SK-I-55)
Affinity DataKi:  2.80nMAssay Description:Displacement of [125I]-Tyr-SRIF 14 from human SST4 receptor expressed in membrane measured after 90 mins by gamma counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSomatostatin receptor type 4(Homo sapiens (Human))
Board of Trustees of The Southern Illinois University

US Patent
LigandPNGBDBM523764(US11136312, Compound SK-I-55)
Affinity DataEC50:  6nMAssay Description:Agonist activity at recombinant human SST4 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated cAMP production measured...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed