BDBM242743 US10030025, Compound 6::US10836768, Cpd no 6::US11731974, Compound 6::US9422299, 6::US9987274, Compound 6

SMILES C[C@H]1N(CCn2c1nnc2-c1nc(C)ns1)C(=O)c1ccc(F)c(Cl)c1

InChI Key InChIKey=DMCGPNZWXATPEH-MRVPVSSYSA-N

Data  16 KI  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 242743   

TargetSubstance-K receptor(Human)
Ogeda

US Patent
LigandPNGBDBM242743(US10030025, Compound 6 | US10836768, Cpd no 6 | US...)
Affinity DataKi:  2.50E+4nMAssay Description:Human NK-2 The affinity of compounds of the invention for the NK-2 receptor was evaluated in CHO recombinant cells which express the human NK-2 recep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetSubstance-K receptor(Human)
Ogeda

US Patent
LigandPNGBDBM242743(US10030025, Compound 6 | US10836768, Cpd no 6 | US...)
Affinity DataKi:  2.50E+4nM ΔG°:  -6.27kcal/molepH: 7.4 T: 25°CAssay Description:The affinity of compounds of the invention for the NK-2 receptor was evaluated in CHO recombinant cells which express the human NK-2 receptor. Membra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetSubstance-K receptor(Human)
Ogeda

US Patent
LigandPNGBDBM242743(US10030025, Compound 6 | US10836768, Cpd no 6 | US...)
Affinity DataKi:  2.50E+4nMAssay Description:The affinity of compounds of the invention for the NK-2 receptor was evaluated in CHO recombinant cells which express the human NK-2 receptor. Membra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetSubstance-K receptor(Human)
Ogeda

US Patent
LigandPNGBDBM242743(US10030025, Compound 6 | US10836768, Cpd no 6 | US...)
Affinity DataKi:  2.50E+4nMAssay Description:The affinity of compounds of the invention for the NK-2 receptor was evaluated in CHO recombinant cells which express the human NK-2 receptor. Membra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetSubstance-K receptor(Human)
Ogeda

US Patent
LigandPNGBDBM242743(US10030025, Compound 6 | US10836768, Cpd no 6 | US...)
Affinity DataKi:  2.50E+4nM ΔG°:  -6.27kcal/molepH: 7.4 T: 25°CAssay Description:The affinity of compounds of the invention for the NK-2 receptor was evaluated in CHO recombinant cells which express the human NK-2 receptor. Membra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent