BDBM50231794 CHEMBL4071549::US11725000, Compound 112
SMILES CCOc1cccc(Cn2cc(ccc2=O)-c2cc(nc(n2)S(C)(=O)=O)C(F)(F)F)c1
InChI Key InChIKey=ZVVOOIIIAPSTAU-UHFFFAOYSA-N
Data 2 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50231794
TargetSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial(Human)
National Institute of Biological Sciences, Beijing
US Patent
National Institute of Biological Sciences, Beijing
US Patent
Affinity DataEC50: 5.01E+5nMAssay Description:In order to identify the target protein of tTC09 apoptosis inhibitors, we synthesized two sets of probes for target identification based on the SAR s...More data for this Ligand-Target Pair
TargetSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial(Human)
National Institute of Biological Sciences, Beijing
US Patent
National Institute of Biological Sciences, Beijing
US Patent
Affinity DataEC50: 110nMAssay Description:Inhibition of SDHB in human U2OS cells over-expressing Bim assessed as inhibition of apoptosis preincubated for 1 hr followed by doxycyclin addition ...More data for this Ligand-Target Pair