BDBM50127174 CHEMBL3628599
SMILES CN1CCN(CC1)C(=O)c1cccc(Cn2nnc3c2C(=O)c2ccccc2C3=O)c1
InChI Key InChIKey=XHMWOYOVGULXFN-UHFFFAOYSA-N
Data 12 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50127174
TargetTryptophan 2,3-dioxygenase(Homo sapiens (Human))
National Health Research Institutes
Curated by ChEMBL
National Health Research Institutes
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of recombinant human TDO expressed in Escherichia coli incubated for 1 hr measured by fluorescence assayMore data for this Ligand-Target Pair
TargetTryptophan 2,3-dioxygenase(Homo sapiens (Human))
National Health Research Institutes
Curated by ChEMBL
National Health Research Institutes
Curated by ChEMBL
Affinity DataIC50: 36nMAssay Description:Inhibition of TDO (unknown origin) assessed as reduction in L-kynurenine formation using L-tryptophan as substrate incubated for 30 mins microplate s...More data for this Ligand-Target Pair
TargetTryptophan 2,3-dioxygenase(Homo sapiens (Human))
National Health Research Institutes
Curated by ChEMBL
National Health Research Institutes
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of TDO (unknown origin)More data for this Ligand-Target Pair