BDBM223102 N-(2-chloro-6-methylphenyl)-2-((2-methyl-6-((1-(methylsulfonyl)pyrrolidin-3-yl)amino)-pyrimidin-4-yl)amino)thiazole-5-carboxamide (5i)
SMILES Cc1nc(NC2CCN(C2)S(C)(=O)=O)cc(Nc2ncc(s2)C(=O)Nc2c(C)cccc2Cl)n1
InChI Key InChIKey=LTQIPTSOJUTHQH-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 223102
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences
Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences
Affinity DataIC50: 0.293nMpH: 7.5 T: 2°CAssay Description:ABL activity assays were performed in 384-well plate using the FRET-based Z'-Lyteassay system and Tyr-2 peptide substrate according to the manufa...More data for this Ligand-Target Pair