BDBM213448 US9278981, 40
SMILES O[C@@H]1CCN(C1)c1ncc(cc1-c1ccccn1)C(=O)Nc1ccc(OC(F)(F)F)cc1
InChI Key InChIKey=PXNYQMOBCTVEKM-MRXNPFEDSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 213448
Affinity DataIC50: 2.20nMpH: 7.5 T: 2°CAssay Description:The assay plates were prepared by addition of 50 nL per well of compound solution in 90% DMSO. The kinase reactions were started by stepwise addition...More data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMpH: 7.5 T: 2°CAssay Description:For determination of ABL kinase activity, the radiometric filter-binding assay was used. The assay was performed by mixing 10 uL of the compound pre-...More data for this Ligand-Target Pair