BDBM174015 US9688661, 4-(6-Aminopyrimidin-4-yl)-1-(5-chloro-2-ethylphenyl)-1H-pyrrole-2-carboxamide (compd 235)

SMILES CCc1ccc(Cl)cc1-c1cn(cc1C(N)=O)-c1cc(N)ncn1

InChI Key InChIKey=PJQOCKSDYYBJLI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 174015   

TargetTyrosine-protein kinase JAK1 [861-1152](Homo sapiens (Human))
Nerviano Medical Sciences

US Patent
LigandPNGBDBM174015(US9688661, 4-(6-Aminopyrimidin-4-yl)-1-(5-chloro-2...)
Affinity DataIC50:  79nMAssay Description:Assays were performed with the JAK1 kinase domain (residues 861-1152 of the 1154 amino acid long full-length sequence, accession number P23458 of Uni...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent