BDBM125906 US8765727, 9

SMILES Clc1cnc2Nc3cccc(CCOc4cccc(CCNc1n2)c4)c3

InChI Key InChIKey=DDEPHNOBUQYIBZ-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 125906   

TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM125906(US8765727, 9)
Affinity DataIC50:  55nMpH: 7.8 T: 2°CAssay Description:One or more compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., A...More data for this Ligand-Target Pair
In DepthDetails US Patent