BDBM50538445 CHEMBL4634723
SMILES [H][C@]12CN(c3ccc(Nc4nc(cn5ccnc45)-c4ccc5cn[nH]c5c4)cc3)[C@]([H])(CO1)C2
InChI Key InChIKey=OIGZWMOTUFTZAL-PMACEKPBSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50538445
Affinity DataIC50: 5nMAssay Description:Inhibition of SYK (unknown origin) using XL665-labeled peptide as substrate in presence of ATP measured after 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.50E+3nMAssay Description:Inhibition of SYK in human whole blood assessed as reduction in anti-FCepsilonR1 mAb-induced basophil activation by measuring decrease in CD63 surfac...More data for this Ligand-Target Pair
Affinity DataEC50: 113nMAssay Description:Inhibition of SYK in human Ramos cells assessed as reduction in antihuman IgM F(ab)2-induced phosphorylation of BLNK at Y96 residue preincubated for ...More data for this Ligand-Target Pair