BDBM50175583 ACP-196::Acalabrutinib::US10239883, Example 6::US10793576, Example ACP-196::US10919899, ACP-196::US10934296, Example 6::US11420975, Acalabrutinlb::US9758524, Example 6
SMILES [H][C@]1(CCCN1C(=O)C#CC)c1nc(-c2ccc(cc2)C(=O)Nc2ccccn2)c2c(N)nccn12
InChI Key InChIKey=WDENQIQQYWYTPO-IBGZPJMESA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50175583
TargetTyrosine-protein kinase TXK(Homo sapiens (Human))
Dongguan Zhenxing-Beite Medicine Technology
US Patent
Dongguan Zhenxing-Beite Medicine Technology
US Patent
Affinity DataIC50: 5.00E+3nMAssay Description:The inhibitory activities of the compound to Tec, Txk, and ITK of human were performed by Eurofins Pharma Discovery Services UK Limited (UK) of the U...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase TXK(Homo sapiens (Human))
Dongguan Zhenxing-Beite Medicine Technology
US Patent
Dongguan Zhenxing-Beite Medicine Technology
US Patent
Affinity DataIC50: 368nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged TXK (260 to 527 residues) expressed in baculovirus expression system using tyrosine-6 peptide a...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase TXK(Homo sapiens (Human))
Dongguan Zhenxing-Beite Medicine Technology
US Patent
Dongguan Zhenxing-Beite Medicine Technology
US Patent
Affinity DataKd: 24nMAssay Description:Binding affinity to TXK (unknown origin) assessed as dissociation constant by KINOMEscan analysisMore data for this Ligand-Target Pair