BDBM50118750 2-(Oxalyl-amino)-6-phenethyl-4,5,6,7-tetrahydro-thieno[2,3-c]pyridine-3-carboxylic acid::CHEMBL140120

SMILES OC(=O)C(=O)Nc1sc2CN(CCc3ccccc3)CCc2c1C(O)=O

InChI Key InChIKey=ZIMJSFGMHLCHIV-UHFFFAOYSA-N

Data  9 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50118750   

LigandPNGBDBM50118750(2-(Oxalyl-amino)-6-phenethyl-4,5,6,7-tetrahydro-th...)
Affinity DataKi:  270nMAssay Description:Inhibition of PTP1B (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM50118750(2-(Oxalyl-amino)-6-phenethyl-4,5,6,7-tetrahydro-th...)
Affinity DataKi:  270nMpH: 5.5Assay Description:Inhibitory effect against recombinant human protein-tyrosine phosphatase 1B (PTP1B), using p-nitrophenyl phosphate substrate at pH 5.5.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50118750(2-(Oxalyl-amino)-6-phenethyl-4,5,6,7-tetrahydro-th...)
Affinity DataKi:  270nMpH: 5.5Assay Description:Inhibition of human recombinant PTP1B (1 to 321 residues) catalytic domain expressed in Escherichia coli BL21 (DE3) cells using p-nitrophenyl phospha...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50118750(2-(Oxalyl-amino)-6-phenethyl-4,5,6,7-tetrahydro-th...)
Affinity DataKi:  3.20E+3nMAssay Description:Inhibition of human recombinant Protein-tyrosine phosphatase 1B.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50118750(2-(Oxalyl-amino)-6-phenethyl-4,5,6,7-tetrahydro-th...)
Affinity DataKi:  3.20E+3nMAssay Description:Inhibition of human recombinant Protein-tyrosine phosphatase 1B.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed