BDBM50223647 CHEMBL112366

SMILES Nc1cc2CCN3c2c(c1)C(=N[C@@H](NC(=O)c1ccncc1)C3=O)c1ccccc1

InChI Key InChIKey=KUPGNWKDDKVLPV-NRFANRHFSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50223647   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50223647(CHEMBL112366)
Affinity DataIC50:  270nMAssay Description:Inhibition of phosphodiesterase 4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50223647(CHEMBL112366)
Affinity DataIC50:  500nMAssay Description:Inhibition of phosphodiesterase type 4 isozyme (PDE4) from the U937 human cell line.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed