BDBM536209 (R)-1-((2S,4R)-4-hydroxy-2-(1-oxa-2,4-diazaspiro[4.4]non-2-en-3-yl)pyrrolidin-1-yl)-3-methyl-2-(3-methylisoxazol-5-yl)butan-1-one::US11242344, Example 127.2

SMILES CC(C)[C@@H](C(=O)N1C[C@H](O)C[C@H]1C1=NOC2(CCCC2)N1)c1cc(C)no1

InChI Key InChIKey=AGJJNPYHMLNPDT-IJEWVQPXSA-N

Data  2 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 536209   

Targetvon Hippel-Lindau disease tumor suppressor(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM536209((R)-1-((2S,4R)-4-hydroxy-2-(1-oxa-2,4-diazaspiro[4...)
Affinity DataIC50:  7.32E+4nMAssay Description:The VHL NanoBRET™ Target Engagement Assay analyzes the apparent affinity of test compounds for VHL in cells by competitive displacement of a VHL Nano...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent