BDBM110972 US8614253, 3-3::US8614253, 43-10::US9241942, 3-3::US9963434, Compound 3-3

SMILES Oc1c(F)cc(cc1C=O)-c1cccs1

InChI Key InChIKey=ZODKJLYQIFWFAO-UHFFFAOYSA-N

Data  5 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 110972   

TargetSerine/threonine-protein kinase/endoribonuclease IRE1(Homo sapiens (Human))
Mannkind

US Patent
LigandPNGBDBM110972(US8614253, 3-3 | US8614253, 43-10 | US9241942, 3-3...)
Affinity DataEC50:  7.00E+4nMAssay Description:Initial cell-based XBP-1 mRNA splicing assays confirmed IRE-1α inhibition with several potent 5-bromo and 6 bromo o-vanillins. HEK293 cells were...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent