BDBM50155152 4-Amino-N-(1-aza-tricyclo[3.3.1.1*3,7*]dec-4-yl)-5-chloro-2-methoxy-benzamide::BDBM50155154::CHEMBL295155::SC-51718

SMILES COc1cc(N)c(Cl)cc1C(=O)NC1C2CC3CC1CN(C3)C2

InChI Key InChIKey=LBXVOPLYLDLZEV-OQONKZOOSA-N

Data  5 KI  4 IC50  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50155152   

Target5-hydroxytryptamine receptor 4(GUINEA PIG)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50155152(4-Amino-N-(1-aza-tricyclo[3.3.1.1*3,7*]dec-4-yl)-5...)
Affinity DataEC50:  262nMAssay Description:Effective concentration required towards 5-hydroxytryptamine 4 receptor in guinea pig striatum using [3H]GR-113808 as the radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(RAT)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50155152(4-Amino-N-(1-aza-tricyclo[3.3.1.1*3,7*]dec-4-yl)-5...)
Affinity DataEC50:  538nMAssay Description:Compound was evaluated in vivo for the antagonistic activity towards 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 4(GUINEA PIG)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50155152(4-Amino-N-(1-aza-tricyclo[3.3.1.1*3,7*]dec-4-yl)-5...)
Affinity DataEC50:  538nMAssay Description:Effective concentration required towards 5-hydroxytryptamine 4 receptor in guinea pig striatum using [3H]GR-113808 as the radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(RAT)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50155152(4-Amino-N-(1-aza-tricyclo[3.3.1.1*3,7*]dec-4-yl)-5...)
Affinity DataEC50:  538nMAssay Description:Compound was evaluated for the agonistic activity towards 5-hydroxytryptamine 4 receptor using the rat tunica muscularis mucosae (TMM) esophagus stri...More data for this Ligand-Target Pair
In DepthDetails Article