BDBM50527022 CHEMBL4590255
SMILES CC(=O)NCCN(Cc1ccccc1)C(=O)c1c2COc3ccc(Br)cc3-c2nn1C
InChI Key InChIKey=KFKHUDFDKQBYKY-UHFFFAOYSA-N
Data 2 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50527022
TargetBile acid receptor(Human)
Genomics Institute of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Genomics Institute of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Affinity DataEC50: 6.00E+3nMAssay Description:Agonist activity at GST-tagged human FXR-LBD (193 to 472 residues) using biotinylated SRC-1 peptide as substrate incubated for 1 hrs by HTRF assayMore data for this Ligand-Target Pair
TargetBile acid receptor(Human)
Genomics Institute of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Genomics Institute of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Affinity DataEC50: >2.00E+4nMAssay Description:Agonist activity at FXR transfected in human HEK293T cells o-expressing pGL3/hBSEP/luc incubated for 24 hrs by Steady-Glo reagent based luciferase re...More data for this Ligand-Target Pair