BDBM261648 N-(4-(3-((tert-butyldiphenylsilyl)ethynyl)phenyl)thiazol-2-yl)-4-((4-methylpiperazin-1-yl)methyl)benzamide::US9708279, 25
SMILES CN1CCN(Cc2ccc(cc2)C(=O)Nc2nc(cs2)-c2cccc(c2)C#C[Si](c2ccccc2)(c2ccccc2)C(C)(C)C)CC1
InChI Key InChIKey=FPNCZMUVAVKMID-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 261648
Affinity DataIC50: 870nMpH: 7.5 T: 25°CAssay Description:GST-tagged recombinant wild-type or L1196M mutated ALK kinase (rALK) was expressed in Sf9 insect cells using the pBacPAK baculovirus vector system (C...More data for this Ligand-Target Pair
Affinity DataIC50: 1.70E+3nMpH: 7.5 T: 25°CAssay Description:GST-tagged recombinant wild-type or L1196M mutated ALK kinase (rALK) was expressed in Sf9 insect cells using the pBacPAK baculovirus vector system (C...More data for this Ligand-Target Pair