BDBM273175 (R)-N-benzyl-1-(5-oxo-7-trifluoromethyl-5H-[1,3,4]thiadiazolo[3,2-a]pyrimidin-2-yl)pyrrolidine-2-carboxamide::US10065972, Example 642
SMILES FC(F)(F)c1cc(=O)n2nc(sc2n1)N1CCC[C@@H]1C(=O)NCc1ccccc1
InChI Key InChIKey=QZJVRPSHTOHCMT-GFCCVEGCSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 273175
TargetKynurenine/alpha-aminoadipate aminotransferase, mitochondrial(Human)
Mitsubishi Tanabe Pharma
US Patent
Mitsubishi Tanabe Pharma
US Patent
Affinity DataIC50: 78nMpH: 8.0Assay Description:The inhibitory action of the test compound on human recombinant KAT-II was determined by the following method.To a reaction mixture (45 μL) cont...More data for this Ligand-Target Pair