BDBM306754 N-(2-((5-((1R,3R)-2-(2,2-difluoroethyl)-3-methyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-yl)-4-methoxypyridin-2-yl)oxy)ethyl)-3-fluoropropan-1-amine::US10149839, Example 40
SMILES COc1cc(OCCNCCCF)ncc1[C@H]1N(CC(F)F)[C@H](C)Cc2c1[nH]c1ccccc21
InChI Key
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 306754
Affinity DataIC50: 0.170nMAssay Description:The ability of compounds to down-regulate Estrogen Receptor (ER) numbers was assessed in a cell based immuno-fluorescence assay using the MCF-7 human...More data for this Ligand-Target Pair
Affinity DataIC50: 1.70nMAssay Description:Compounds were dosed directly from a compound source microplate containing serially diluted compound (4 wells containing 10 mM, 0.1 mM, 1 mM and 10 n...More data for this Ligand-Target Pair