BDBM362167 (S)-3-(5-chloro-2-(cyclopropyl((2,6-diamino-5-cyanopyrimidin-4-yl)amino)methyl)-4-oxoquinazolin-3(4H)-yl)-5-fluorobenzamide::US10221197, Compound 161
SMILES NC(=O)c1cc(F)cc(c1)-n1c(nc2cccc(Cl)c2c1=O)[C@@H](Nc1nc(N)nc(N)c1Cl)C1CC1
InChI Key InChIKey=PXDJKIJBWDMRJE-KRWDZBQOSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 362167
Affinity DataIC50: 2.00E+3nMAssay Description:TR-FRET monitored the formation of 3,4,5-inositol triphosphate molecule that competed with fluorescently labeled PIP3 for binding to the GRP-1 plecks...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Human)
Gilead Sciences
US Patent
Gilead Sciences
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TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Gilead Sciences
US Patent
Gilead Sciences
US Patent