BDBM464537 US10793549, Compound G-23
SMILES COc1cc(C)[nH]c(=O)c1CNC(=O)c1cc(cc2n(cc(O)c12)S(=O)(=O)C1(CC=C)CC1)-c1cnc(nc1)N1CCNCC1
InChI Key InChIKey=VLGDZXFHUXKWIS-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 464537
TargetHistone-lysine N-methyltransferase EZH2 [Y641F]/Polycomb protein EED/Polycomb protein SUZ12(Human)
Shanghai Haiyan Pharmaceutical Technology
US Patent
Shanghai Haiyan Pharmaceutical Technology
US Patent
Affinity DataIC50: 5nMAssay Description:Recombinant PRC2 (EZH2-Y641F) was purchased from Active motif company, S-adenosyl-methionine (SAM) and Poly-L-lysine (PLL) were purchased from Sigma-...More data for this Ligand-Target Pair