BDBM50168829 CHEMBL3805130
SMILES NC(=O)c1cncc(OCc2cccc(NC(=O)c3cc4ccccc4o3)c2)c1
InChI Key InChIKey=LSMDHIVSLHLTFA-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50168829
Affinity DataIC50: 9.93E+3nMAssay Description:Inhibition of recombinant human N-terminal His-tagged SIRT1 (1 to 747 residues) expressed in Escherichia coli using Ac-RHK-K(Ac)-AMC as substrate inc...More data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Human)
University of Minnesota
Curated by ChEMBL
University of Minnesota
Curated by ChEMBL
Affinity DataIC50: 2.37E+3nMAssay Description:Inhibition of human SIRT3 (102 to 399 residues) expressed in Escherichia coli using Ac-RHK-K(Ac)-AMC as substrate incubated for 2 hrs by fluorescence...More data for this Ligand-Target Pair
Affinity DataIC50: 65nMAssay Description:Inhibition of recombinant human C-terminal His-tagged SIRT2 (50 to 389 residues) expressed in Escherichia coli using Ac-RHK-K(Ac)-AMC as substrate in...More data for this Ligand-Target Pair