BDBM50224873 (6S,11R)-3-cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocine-8-carboxylic acid [2-(4'-methoxy-biphenyl-4-yl)-ethyl]-amide::CHEMBL249985

SMILES COc1ccc(cc1)-c1ccc(CCNC(=O)c2ccc3CC4[C@H](C)[C@](C)(CCN4CC4CC4)c3c2)cc1

InChI Key InChIKey=XREFQBQBSMEQOG-HUSBTFBPSA-N

Data  6 KI  1 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50224873   

TargetMu-type opioid receptor(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM50224873((6S,11R)-3-cyclopropylmethyl-6,11-dimethyl-1,2,3,4...)
Affinity DataIC50:  24nMAssay Description:Antagonist activity at human mu opioid receptor expressed in CHO cell membrane assessed as inhibition of DAMGO induced [35S]GTP-gamma-S bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed