BDBM50432578 CHEMBL2347165

SMILES Fc1ccc2[nH]cc(CCCNCc3ccccc3)c2c1

InChI Key InChIKey=RTLQUOXHRQJNMY-UHFFFAOYSA-N

Data  2 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50432578   

TargetMyeloperoxidase(Human)
Free University of Brussels

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50432578BDBM50432578(CHEMBL2347165)
Affinity DataIC50: 13nMAssay Description:Inhibition of human recombinant MPO-mediated taurine chlorination after 5 mins by microplate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMyeloperoxidase(Human)
Free University of Brussels

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50432578BDBM50432578(CHEMBL2347165)
Affinity DataIC50: 13nMAssay Description:Inhibition of MPO chlorination activity (unknown origin) assessed as taurine chloramine formation after 5 mins in presence of H2O2/Cl- by HTS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2018
Entry Details Article
PubMed
TargetMyeloperoxidase(Human)
Free University of Brussels

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50432578BDBM50432578(CHEMBL2347165)
Affinity DataIC50: 30nMAssay Description:Inhibition of human recombinant MPO-mediated LDL oxidation after 5 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed