BDBM50547862 CHEMBL4792402
SMILES CC(=O)Nc1ccc2nc(NC(=O)c3[nH]c(C)c(Cl)c3Cl)sc2c1
InChI Key InChIKey=AAWYAFMPUFDEST-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50547862
Affinity DataIC50: 9.5nMAssay Description:Inhibition of Escherichia coli DNA gyrase using relaxed pNO1 plasmid DNA as substrate incubated for 30 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetDNA topoisomerase 4 subunit A/B(Staphylococcus aureus)
University of Ljubljana
Curated by ChEMBL
University of Ljubljana
Curated by ChEMBL
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of Staphylococcus aureus DNA topoisomerase 4 using supercoiled pNO1 plasmid DNA as substrate incubated for 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 400nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase using relaxed pNO1 plasmid DNA as substrate incubated for 30 mins by fluorescence assayMore data for this Ligand-Target Pair